AGENT WITH ANTITUMOUR AND ANTIMETASTATIC ACTIVITY, ANTI-INFLAMMATORY AND ANTIALLERGIC ACTION Russian patent published in 2019 - IPC A61K31/505 A61P35/00 A61P37/08 A61P29/00 A61P37/02 

Abstract RU 2686672 C1

FIELD: chemistry.

SUBSTANCE: group of inventions relates to the chemical-pharmaceutical industry and is an antitumour and antimetastatic agent possessing anti-inflammatory and anti-allergenic action, which is 2-isobutyl-4,6-dimethyl-5-oxypyrimidine hydrochloride of formula 1

. Invention also includes use of compound of formula 1 as an antitumour agent for adjuvant anticancer immunotherapy together with doxorubicin, as well as an antiallergenic preventive agent in seasonal allylic infections. Group of inventions provides higher anti-tumor activity and can be used as an independent anticancer agent and simultaneous increase in the effectiveness of cytostatic treatment of oncological patients.

EFFECT: new agent has no undesirable side effects inherent in fluorinated pyrimidines and anthracycline antibiotics.

3 cl, 5 tbl, 5 ex

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RU 2 686 672 C1

Authors

Kovalenko Larisa Petrovna

Nikitin Sergej Vasilevich

Durnev Andrej Dmitrievich

Gudasheva Tatyana Aleksandrovna

Dates

2019-04-30Published

2018-07-20Filed