METHOD OF 2,3-DIALKYLQUINOLINES PRODUCTION Russian patent published in 2019 - IPC C07D215/04 

FIELD: technological processes.

SUBSTANCE: invention describes a method of producing 2,3-dialkylquinolines by reacting aniline with aldehydes in the presence of a zeolite based catalyst, method is characterized by that catalyst used is zeolite Y in H-form, reaction of aniline with aliphatic aldehydes (propionic or oily) is carried out in presence of 10–20 wt% catalyst, in molar ratio of aniline:aldehyde = 1:1–2, in autoclave at 70–160 °C for 6 hours, in a solution of chlorobenzene.

EFFECT: method simplifies synthesis of quinoline derivatives and reduces energy and material consumption of the heterocyclisation process.

1 cl, 1 tbl, 2 ex