FIELD: organic chemistry.
SUBSTANCE: invention relates to the field of organic chemistry, namely to a method for producing mono-methylquinolines, widely used in the manufacture of medicines, fungicides and herbicides, metal corrosion inhibitors, extractants and sorbents, dyes and high-boiling solvents. The method consists in the interaction of ethylene glycol with aniline in the presence of granular zeolite H-ZSM-5mmm of a high degree of crystallinity having a hierarchical (micro-meso-macro-porous) structure at 280-450°C, atmospheric pressure, volumetric feed rate (w) 3.0 h-1, molar ratio of aniline:ethylene glycol equal to 1:3, ethylene glycol is fed into the reactor without a solvent or in the form of a 20% solution in alcohol.
EFFECT: a simple effective heterogeneous-catalytic method for the synthesis of mono-methylquinolines has been developed, which reduces the energy and material consumption of the heterocyclization process.
2 cl, 1 tbl, 6 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PRODUCING QUINOLINES | 2022 |
|
RU2786740C1 |
| METHOD FOR OBTAINING QUINOLINES IN THE PRESENCE OF HIERARCHICAL ZEOLITE H-Y-mmm | 2021 |
|
RU2789408C1 |
| METHOD OF PRODUCING QUINOLINE BY SKRAUP REACTION IN PRESENCE OF HIERARCHICAL ZEOLITE H-ZSM-5MMM | 2020 |
|
RU2740912C1 |
| METHOD OF PRODUCING QUINOLINES BY SKRAUP REACTION IN PRESENCE OF HIERARCHICAL ZEOLITE H-YMMM | 2019 |
|
RU2738603C1 |
| METHOD FOR JOINT PRODUCTION OF N-PROPYLANILINE AND 2-ETHYL-3-METHYLQUINOLINE | 2022 |
|
RU2797946C1 |
| METHOD FOR OBTAINING 3-METHYL-2-ETHYLQUINOLINE | 2023 |
|
RU2803740C1 |
| METHOD OF PRODUCING 2,3-DIALKYLQUINOLINES | 2018 |
|
RU2690535C1 |
| METHOD OF PRODUCING 2,3-DIALKYLQUINOLINES | 2018 |
|
RU2688228C1 |
| METHOD OF 2,3-DIALKYLQUINOLINES PRODUCTION | 2018 |
|
RU2688198C1 |
| METHOD OF 2,3-DIALKYLQUINOLINES PRODUCTION | 2018 |
|
RU2687974C1 |
