METHOD FOR RAT PERIODONTIUM BONE BLOOD FLOW VELOCITY DETERMINATION IN EXPERIMENT Russian patent published in 2019 - IPC G09B23/28 A61B5/26 A61B8/06 

FIELD: medicine.

SUBSTANCE: invention refers to experimental medicine and can be used to determine rat periodontium bone blood flow velocity in experiment. Blood flow velocity of the analysed periodontium segment is determined by laser Doppler flowmetry (LDF) and ultrasonic dopplerography (USDG). Acetylcholine chloride (AC) on the analysed periodontium section with exposure of 1 min. That is followed by determining the maximum periodontium blood flow velocity by methods LDF and USDG. Further, the periodontal bone blood flow velocity is determined by the formula Ubone=U1-(U2-U1)×L1/(L2-L1), where Ubone is periodontal blood flow velocity value, ml/s/cm³; L1 – value of periodontium blood flow before sample with AC, measured by method LDF, perfusion units; U1 is the periodontal blood flow velocity value before the sample with AC, measured by method USDG, ml/s/cm³; L2 – maximum value of periodontium blood flow after sample with AC, measured by method LDF, perfusion units; U2 – maximum value of periodontium blood flow after sample with AC, measured by method USDG, ml/s/cm³.

EFFECT: method provides non-invasive studies on the dynamics of periodontal bone blood flow with normal and disturbed microcirculation by determining the periodontium bone blood velocity using a mathematical expression.

1 cl, 2 dwg