METHOD OF PRODUCING CERAMIC GRANULES FOR BONE TISSUE REGENERATION Russian patent published in 2019 - IPC A61L27/00 A61L27/12 

Abstract RU 2695342 C1

FIELD: chemistry.

SUBSTANCE: invention relates to a method of producing ceramic material and specifically to a method of producing ceramic granules. Method of producing ceramic granules for bone tissue regeneration, having the following phase composition in certain proportions: octocalcium phosphate, hydroxyapatite, calcium carbonate. Method includes step of transformation of granules of calcium carbonate into dicalcium phosphate dihydrate in solution A, further, obtained granules are washed in distilled water and dried; stage of transformation of granules of dicalcium phosphate dihydrate into octacalcium phosphate in solution B, further, obtained granules are washed in distilled water and dried, under certain conditions, where solution A is an aqueous solution of ammonium dihydroorthophosphate, and solution B is an aqueous solution of sodium acetate.

EFFECT: method described above enables to obtain ceramic granules of octacalcium phosphate based on calcium carbonate of specified size with developed microstructure, high specific surface area and high pH values for formation of porous matrices.

3 cl, 5 dwg, 3 tbl, 13 ex

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RU 2 695 342 C1

Authors

Bozo Ilya Yadigerovich

Komlev Vladimir Sergeevich

Fedotov Aleksandr Yurevich

Dates

2019-07-23Published

2018-04-19Filed