FIELD: chemistry; medicine; pharmacology.
SUBSTANCE: invention refers to chemistry of organic compounds, pharmacology and medicine, namely to compound of 2-phenylethylamide N-(p-hydroxyphenylacetyl)phenylalanine of the formula given below, which is an antagonist of tachykinin receptors (NK1, NK2 and NK3).
EFFECT: invention also relates to a method of producing said compound, use thereof for preventing and/or treating disorders associated with activity of first, first and second tachykinin receptors, second and third types, pharmaceutical compositions containing same, as well as methods for preventing and/or treating disorders associated with tachykinin receptor activity.
13 cl, 9 tbl, 8 ex
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| NEW MULTITARGET PREPARATION FOR TREATING DISEASES IN MAMMALS | 2017 |
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RU2690188C2 |
| 1-[(4-[BENZOYL(METHYL)AMINO]-3-(PHENYL)BUTYL] AZETIDINE DERIVATIVES FOR TREATMENT OF GASTROINTESTINAL DISORDERS | 2007 |
|
RU2439067C2 |
| NEW ANTAGONISTS NK AND NK | 2006 |
|
RU2419609C2 |
| (R)-3-(1H-INDOLE-3-YL)-1-[N-(2-METHOXYBENZYL)ACETYLAMINO]-2- -[N-(2-(4-PIPERIDINE-1-YL)PIPERIDINE-1-YL)ACETYL)AMINO]PROPANE DIHYDROCHLORIDE TRIHYDRATE AND PHARMACEUTICAL COMPOSITION | 1995 |
|
RU2151769C1 |
| 3-AZETHIDINYLALKYLPIPERIDINES OR PYRROLIDINES AS TACHYKININE ANTAGONISTS, METHODS OF THEIR SYNTHESIS, INTERMEDIATE COMPOUNDS, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND METHOD OF TREATMENT | 1996 |
|
RU2158264C2 |
| HETERO-ARYL DERIVATIVES AS SUPER LIGANDS FOR NOCICEPTIN ORL-1 RECEPTOR | 2002 |
|
RU2327698C2 |
| COMPOUND, PHARMACEUTICAL COMPOSITION | 1999 |
|
RU2237060C2 |
| COMPOUND SALTS, MEDICINAL AGENT, COMPOSITION, METHOD OF PROPHYLAXIS, METHOD OF TREATMENT | 1998 |
|
RU2190615C2 |
| ENANTIOMERS OF AROMATIC NITROGEN-CONTAINING DERIVATIVES AND THEIR SALTS WITH INORGANIC OR ORGANIC ACIDS AND A METHOD OF THEIR SYNTHESIS | 1990 |
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RU2114828C1 |
| NONPEPTIDE ANTAGONISTS OF TACHIKININ RECEPTORS | 1994 |
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RU2140921C1 |
