FIELD: medicine.
SUBSTANCE: invention refers to medicine, namely to dermatology, and can be used for differential diagnosis of plaque psoriasis with other chronic skin diseases. Method involves immunohistochemical examination of a biopsy material of an involved skin area by determining expression of IL-36γ in the epidermis by means of a light microscope. When determining expression of IL-36γ in form of specific dyeing ≥ 4 rows of epidermis cells diagnose plaque psoriasis, when staining 2 to 3 rows – diagnosed is doubtful, and when painting ≤ 1 row – the diagnosis of psoriasis is excluded.
EFFECT: using the given method enables diagnosing plaque psoriasis by determining IL-36γ expression in skin biopsy materials.
1 cl, 1 tbl, 2 ex
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Authors
Dates
2019-10-16—Published
2019-07-15—Filed