FIELD: medicine.
SUBSTANCE: invention refers to medicine, namely to cardiology, and concerns prediction of essential hypertension. That is ensured by isolating DNA from peripheral venous blood of patients, followed by amplification of polymorphous variants CACNA1C G2236129A (rs1006737), CACNA1C G2585485A (rs112532048), CACNA1H G1134967A (rs11865472), CACNA1G G50615794A (rs11079919), CACNB2 C18539252T (rs143326262), RYR2 G237115840T (rs2490389). Depending on the revealed combinations of genotypes, the development of essential hypertension is predicted.
EFFECT: invention enables predicting the development of preclinical hypertension, which, accordingly, enables timely prevention of the disease.
1 cl, 2 tbl, 4 ex
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Authors
Dates
2019-10-21—Published
2019-06-17—Filed