FIELD: medicine; cardiology; biotechnology medical genetics.
SUBSTANCE: invention can be used to predict the risk of developing arterial hypertension in women. DNA from the peripheral venous blood is isolated. The polymorphic loci CERS5, HFE, TBX2 and RGL3 are analyzed. When identifying a combination of genotypes rs7302981 AA CERS5 × rs1799945 CC HFE × rs8068318 CC TBX2 × rs167479 TG RGL3 a high risk of developing arterial hypertension in women is predicted.
EFFECT: method provides new criteria for assessing the risk of developing arterial hypertension in women of Russian nationality who are natives of the Central Black Earth region of the Russian Federation and are not relatives to each other, based on data on the polymorphic loci CERS5, HFE, TBX2 and RGL3.
1 cl, 1 tbl, 4 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF PREDICTING RISK OF DEVELOPING HYPERTENSION BASED ON DATA ON INTERGENIC INTERACTIONS | 2023 |
|
RU2809911C1 |
| METHOD OF PREDICTING RISK OF DEVELOPING HYPERTENSION IN MEN BASED ON RESULTS OF GENETIC TESTING | 2023 |
|
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| METHOD FOR PREDICTION OF RISK OF SEVERE PREECLAMPSIA | 2024 |
|
RU2834809C1 |
| METHOD FOR PREDICTING RISK OF DEVELOPING ESSENTIAL HYPERTENSION IN WOMEN BASED ON GENETIC FACTORS | 2017 |
|
RU2664428C1 |
| METHOD FOR PREDICTING THE RISK OF DEVELOPING PREECLAMPSIA IN WOMEN BASED ON GENETIC MARKERS | 2022 |
|
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|
RU2678441C1 |
| METHOD FOR PREDICTION OF RISK OF ESSENTIAL HYPERTENSION DEVELOPMENT BASED ON MATRIX METAL PROTEINASE GENES COMBINATIONS | 2016 |
|
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| METHOD FOR PREDICTING THE RISK OF DEVELOPING ESSENTIAL HYPERTENSION | 2017 |
|
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| METHOD FOR PREDICTION OF RISK OF DEVELOPING PREECLAMPSIA BASED ON GENETIC TESTING | 2024 |
|
RU2834808C1 |
| METHOD FOR PREDICTING THE RISK OF DEVELOPING HYPERTENSIVE DISORDER BASED ON MOLECULAR AND GENETIC DATA | 2018 |
|
RU2679401C1 |
