FIELD: chemistry.
SUBSTANCE: invention relates to use of a compound which is a negative modulator of kainate receptors of general formula (I), as well as use of a pharmaceutical composition comprising compounds of general formula (I) for treating and/or preventing a depressive disorder, an anxiety disorder and/or a stress-related disorder. In general formula (I), cycle X is independently selected and is phenyl optionally substituted with 1–2 substituents Rx, linker L is independently selected and represents -CH2- or -CH2-O-, cycle A is selected independently and represents a phenyl, 5–6-member saturated or unsaturated heterocycle containing 1–2 N atoms and optionally substituted with 1–2 substitutes selected from halogen and methyl.
Formula (I).
EFFECT: therapy of depression, anxiety disorder and/or stress-related disorder.
15 cl, 3 ex, 10 dwg
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