USE OF N,N"-SUBSTITUTED 3,7-DIAZABICYCLO[3_3_1]NONANES DERIVATIVES FOR DEPRESSION THERAPY Russian patent published in 2020 - IPC A61K31/395 A61K31/444 A61K31/4025 A61P43/00 A61P25/00 A61P25/18 A61P25/22 A61P25/24 

FIELD: chemistry.

SUBSTANCE: invention relates to use of a compound which is a negative modulator of kainate receptors of general formula (I), as well as use of a pharmaceutical composition comprising compounds of general formula (I) for treating and/or preventing a depressive disorder, an anxiety disorder and/or a stress-related disorder. In general formula (I), cycle X is independently selected and is phenyl optionally substituted with 1–2 substituents R^x, linker L is independently selected and represents -CH₂- or -CH₂-O-, cycle A is selected independently and represents a phenyl, 5–6-member saturated or unsaturated heterocycle containing 1–2 N atoms and optionally substituted with 1–2 substitutes selected from halogen and methyl.

Formula (I).

EFFECT: therapy of depression, anxiety disorder and/or stress-related disorder.

15 cl, 3 ex, 10 dwg