DIAGNOSTIC METHOD OF COMATOSE STATE IN CASE OF PNEUMONIA Russian patent published in 2020 - IPC A61B10/00 G01N33/50 

FIELD: medicine.

SUBSTANCE: invention refers to medicine and can be used in therapy. Method for diagnosing a comatose state in pneumonia involves examining a general clinical condition of a patient and a pulmonary tissue prior to treatment by computed tomography, spirography with simultaneous general analysis, wherein blood serum is additionally determined by amount of C-reactive protein, level of TBA-active compounds, activity of catalase, superoxide dismutase, elastase- and trypsin-like proteinases when compared with the control, the discriminant functions Y1 and Y2 are calculated by equations: Y1=-28.8+0.4⋅X1+0.1⋅X2-0.01⋅X3+0.01⋅X4+3.8⋅X5; Y2=-31.0+0.1⋅X1-0.01⋅X2+0.1⋅X3+0.2⋅X4-0.6⋅X5; where X1 is the amount of C-reactive protein, mg/l; X2 – activity of trypsin-like proteinases, nmol BAEE/min⋅ml; X3 – activity of elastase-like proteinases, nmole BANE/min⋅ml; X4 is catalase activity, mcmol/l; X5 – activity of superoxide dismutase, unit/l, and if Y1 value is more than Y2 with ESR growth by 7 times and more as compared to norm (7.6±2.0) mm Hg, increase in amount of C-reactive protein by 100 times and more at norm (0.6±0.07) mg/l, increased level of TBA-active compounds by 4 times and more at norm (3.1±0.4) mc/ml on the background of sharply expressed eosinophilia exceeding norm by 10 times and more at norm (2.4±0.6) %, comatose state is diagnosed in pneumonia with alveolar type of infiltration in pulmonary tissue.

EFFECT: invention provides higher accuracy and effectiveness of diagnosing coma.

1 cl, 4 tbl, 1 ex