METHOD FOR PREDICTING COURSE OF PNEUMONIA WITH ALVEOLAR TYPE OF LUNG TISSUE INFILTRATION Russian patent published in 2021 - IPC G01N33/50 

Abstract RU 2753745 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to therapy. The method for predicting the course of pneumonia is to study a general blood test before and after treatment. At the same time, the amount of C-reactive protein, the activity of catalase, superoxide dismutase, elastase- and trypsin-like proteinases, the activity of a1-proteinase inhibitor, the level of TBA-active compounds, the concentration of bityrosine are additionally determined in the blood serum, and the discriminant functions of Y1 and Y2 are calculated. With a value of Y1 greater than Y2, a decrease in the number of white blood cells by 30% or more, the activity of elastase-like proteinases by 35% or more, the activity of trypsin-like proteinases by 40% or more, the number of eosinophils by 50% or more, ESR by 50% or more, the amount of C-reactive protein by 50% or more, the activity of SOD by 50% or more, the level of TBA-active compounds by 50% or more, the concentration of bityrosine by 50% or more in comparison with the level before treatment, and also with an increase of 20% or more in the activity of the a1-proteinase inhibitor after treatment relative to 30.2±3.1 IU/ml, the prognosis of pneumonia with alveolar infiltration is considered favorable.

EFFECT: invention provides increased accuracy of the prognosis.

1 cl, 1 ex, 4 tbl

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RU 2 753 745 C1

Authors

Kanskaya Natalya Viktorovna

Udut Vladimir Vasilevich

Dyakov Denis Aleksandrovich

Bajkov Aleksandr Nikolaevich

Akbasheva Olga Evgenevna

Udut Elena Vladimirovna

Samojlova Yuliya Gennadevna

Saprina Tatyana Vladimirovna

Denisov Nikita Sergeevich

Olejnik Oksana Alekseevna

Zajtseva Anna Aleksandrovna

Zhujkova Natalya Aleksandrovna

Spirina Lyudmila Viktorovna

Kokorev Oleg Viktorovich

Dates

2021-08-23Published

2020-06-16Filed