DIAGNOSTIC TECHNIQUE FOR AUTOIMMUNE INFLAMMATION IN NEWLY DIAGNOSED SARCOIDOSIS PATIENTS Russian patent published in 2020 - IPC G01N33/53 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely pulmonology, and aims at diagnosing autoimmune inflammation in newly diagnosed patients with sarcoidosis. Method consists in determining the level of autoantibodies to modified citrullinated vimentin (anti-MCV) and B-cell level. If the anti-MCV increase is 10 units/ml and higher, and the CD5 + CD27 level is more than 12.45 %, and if the ratio of naive B cells to the memory cells is more than 2:1, autoimmune inflammation is diagnosed.

EFFECT: use of the invention provides a high level of specificity (88 %) and sensitivity (91 %) and enables the timely prescription of a pathogenetic therapy, which improves clinical course, prevents chronic course and reduces the number of recurrences.

1 cl, 2 dwg, 2 tbl, 2 ex