METHOD FOR DIAGNOSIS OF LIGHT DESYNCHRONOSIS Russian patent published in 2021 - IPC A61B5/00 G01N33/48 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to functional diagnostics, public health and health care, and can be used to assess the severity of light desynchronosis. A total assessment is carried out on a five-point scale, which is characterized by the following actions on patients over 45 years old. Evaluate the ratio of the evening value of the level of total blood cholesterol to the morning value; if the value is greater than one, 1 point is awarded. It is necessary to find the ratio of evening values of low-density lipoproteins to high density lipoproteins, with a value greater than 1.75, 1 point is awarded. The level of the evening value of blood plasma malondialdehyde is estimated, with a value of more than 1.3 mcM/l, 1 point is awarded. On the Beck depression scale, the level of depression is determined, with a value of more than 20, 1 point is awarded, then the ratio of the phase of the circadian rhythm of the axillary temperature determined by cosinor analysis and the patient's age at the time of the study is determined, with a value of more than 0.25 hours/years 1 point is assigned. According to the total assessment of the number of points, the severity of light desynchronosis is determined: high - with a value of 4 to 5 points inclusive, medium - with a value of 3 points, low - with a value of 1 to 2 points inclusive.

EFFECT: invention allows determining the high, medium and low severity of light desynchronosis.

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