FIELD: immunology.
SUBSTANCE: present invention relates to the field of immunology. A method for obtaining an antibody that has a preserved or reduced binding activity to FcγRIIa (Type R) and FcγRIIa (Type Н) and increased binding activity to FcγRIIb is proposed.
EFFECT: present invention can find further application in obtaining antibodies of different specificity with an altered ability to bind both allotypes FcγRIIa and FcγRIIb.
7 cl, 16 dwg, 12 tbl, 9 ex
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