METHOD FOR DETERMINING THE DEGREE OF REGRESSION OF LOCALLY ADVANCED GASTRIC CANCER AFTER NEOADJUVANT CHEMOTHERAPY BY COMPUTED TOMOGRAPHY Russian patent published in 2021 - IPC A61B6/00 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to the diagnostics of oncological diseases, it can be used to determine the degree of regression of locally advanced gastric cancer after neoadjuvant chemotherapy by computed tomography (hereinafter – CT). Before and after neoadjuvant chemotherapy, CT is performed with intravenous bolus injection of a contrast agent in the arterial, portal, and delayed scanning phases with the intake of a gas mixture. The largest paragastric lymph node, which is regarded as metastatic, is measured along the short axis. If all paragastric lymph nodes are regarded as non-metastatic by CT, then the largest paragastric lymph node is measured along the short axis, excluding nodes of groups No. 8 and No. 12. If the size of the lymph node on the short axis is more than 6 mm, then the degree of pathomorphologic regression on CT is set as TRG 0/1. If the size of the lymph node along the short axis is less than 6 mm or equal to 6 mm, then the maximum values of the densitometric density of the gastric tumor in the arterial scanning phase are determined, and with a density of more than 59 HU, the degree of pathomorphologic regression on CT is determined as TRG 1/2, if a density is less than or equal to 59 HU, the regression is determined as TRG 2/3.

EFFECT: method allows determining the degree of regression of locally advanced gastric cancer after neoadjuvant chemotherapy by CT due to the declared CT characteristics of the tumor.

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