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(19)

(11)

2 757 665

(13)

(51)

IPC

A01K67/27(2006-01-01)

C07K16/00(2006-01-01)

C12N15/90(2006-01-01)

(21) (22)

Application

2019112589, 2017-11-03

(24)

Start date

2017-11-03

(22)

Actual filing date

2017-11-03

(45)

Published

2021-10-20

(72)

Inventor

Guo, ChunguangHarris, FaithVoronina, VeraMcwhirter, JohnLevenkova, NatashaMacdonald, LynnTu, NaxinMurphy, Andrew, J.

(73)

Holder

Regeneron Pharmaceuticals, Inc.

ANIMALS OTHER THAN HUMANS WITH CONSTRUCTED LOCUS OF LIGHT LAMBDA CHAIN OF IMMUNOGLOBULIN Russian patent published in 2021 - IPC A01K67/27 C07K16/00 C12N15/90

Abstract RU 2757665 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to the field of biotechnology, in particular, to a mouse, a germ-type genome of which contains endogenous locus of light λ chain of immunoglobulin containing: one or more segments of human Cλ gene, as well as to a method for obtaining it.

EFFECT: invention is effective for the production of an antibody.

21 cl, 21 dwg, 4 tbl, 6 ex

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RU 2 757 665 C2

Authors

Guo, Chunguang

Harris, Faith

Voronina, Vera

Mcwhirter, John

Levenkova, Natasha

Macdonald, Lynn

Tu, Naxin

Murphy, Andrew, J.

Dates

2021-10-20—Published

2017-11-03—Filed