GRANULES USED IN A CELL CULTURE AND METHODS FOR PRODUCTION THEREOF Russian patent published in 2021 - IPC C12N5/00 C12N1/22 B01J8/18 

FIELD: biotechnology.

SUBSTANCE: group of inventions relates to production of dry cell culture media or feeds in the format of granules. Proposed are methods for producing granules of a cell culture medium, a base powder module or a nutrient medium by means of direct granulation. A first dry powder of a cell culture medium, a dry base powder of a nutrient medium, or a dry powder of a nutrient medium is introduced into a rotating disk rotor of an apparatus with a fluidised bed, wherein said first dry powder is preliminarily wetted. A solvent and/or a second dry powder of the cell culture medium, a dry base powder of a nutrient medium or a dry powder of a nutrient medium are then introduced into the rotating disk rotor so as to form a granule. The first dry powder, the second dry powder or the solvent comprises a binding agent, an auxiliary substance, or both thereof. The granules are dried.

EFFECT: inventions allow for direct granulation of powders of cell culture media, feeds or additives applied for cultivation of cells containing 80 to 100 individual components; the granules of media can be easier to handle before reduction, during transportation and operation and/or during reduction.

17 cl, 10 dwg, 9 tbl, 9 ex