FIELD: biotechnology.
SUBSTANCE: invention relates to use of meta-tyrosine to increase specific production, which is the amount of produced polypeptide a day, Chinese hamster ovary CHO-K1 cells, which produces an exogenous polypeptide, as well as producing exogenous polypeptide in CHO-K1 and increasing specific productivity in CHO-K1. Method comprises culturing CHO-K1 in a culture medium containing a meta-tyrosine.
EFFECT: invention increases output of the exogenous polypeptide.
13 cl, 8 dwg, 1 tbl, 2 ex
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