METHOD OF SCREENING EXAMINATION FOR DETECTION OF RISK GROUPS OF DEVELOPING HYPERCOAGULATION STATE IN CONDITIONS OF EXPEDITIONARY WORK IN THE ARCTIC Russian patent published in 2022 - IPC G01N33/86 A61B5/145 

FIELD: medicine.

SUBSTANCE: disclosed is a screening method for detecting risk groups of developing a hypercoagulation state in conditions of expeditionary work in the Arctic. Venous blood is sampled from the expedition members, sailors and shift workers in the Arctic zone. Obtained blood samples are centrifuged at 3,000 rpm for 15 minutes. Automatic analyzer is used to determine the lag-phase time (tLag), the thrombin peak formation time (tPeak), the thrombin peak (Peak) and the endogenous thrombin potential (AUC). If the lag phase (tLag) is less than 7.8 minutes, the thrombin peak formation time (tPeak) is less than 16.7 minutes, the thrombin peak (Peak) is more than 153.7 nM, thrombin endogenous potential (AUC) of more than 1,735.9 nM of the person being tested is considered to be at risk of developing hypercoagulation in conditions of expeditionary work in Arctic.

EFFECT: invention provides objectification of the analyzed feature of hypercoagulation syndrome, increased diagnostic significance of the method and simplified interpretation of results, based on which a judgment is made on the possibility of the presence of hypercoagulation syndrome in conditions of expeditionary work in the Arctic.

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