FIELD: modified proteins.
SUBSTANCE: invention relates to a modified factor H binding protein (fHbp), which is fHbp, or a variant thereof, modified by adding at least one loop of an exogenous peptide; and related nucleic acid, compositions and uses.
EFFECT: modified factor H binding protein (fHbp) can be used to treat or prevent the occurrence of a pathogenic infection or colonization in a subject.
17 cl, 8 dwg, 4 tbl, 2 ex
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