FIELD: tobacco industry.
SUBSTANCE: group of inventions relates to a system for determining the interaction between a test atmosphere and a respiratory tract model, a pump for mixing a gas volume, a piston pump for mixing a gas volume, a connecting structure, a method for modeling the interaction between a test atmosphere and a respiratory tract model, the use of the specified systems, a method for determining a test atmosphere impact on a respiratory tract model, and an aerosol generating device. The system contains: (a) the first pump containing: (i) a chamber made with the possibility of containing the first gas volume containing the test atmosphere; (ii) the first channel made with the possibility of receiving and releasing gas and containing a valve for regulating a gas flow passing through the first channel, wherein the specified valve is made with the possibility of moving between open and closed positions, wherein, in the open position, the specified valve is capable of opening in the direction of the test atmosphere or ambient air; (iii) the second channel made with the possibility of receiving and releasing gas and containing a valve for regulating a gas flow passing through the second channel, wherein the specified valve is made with the possibility of moving between open and closed positions; (iv) a piston plate in the chamber, wherein the specified piston plate contains one or more openings for gas entry or inflow into the chamber, while one or more or each of openings includes a valve made with the possibility of moving between open and closed positions and capable of regulating the gas entry or inflow; (b) the second pump containing: (i) a chamber made with the possibility of containing the second gas volume, while the first and the second gas volumes differ from each other; (ii) a channel made with the possibility of receiving and releasing gas; and (iii) an engine to control the operation of the second pump; (c) a connecting structure used to transfer gas from the first pump to the second pump; and (d) one or more holes in the first pump, or the second pump, or walls of the connecting structure, or in combination of two or more of the specified options, wherein the specified holes are capable of accommodating a module for containing a cell cultivation medium, or for monitoring conditions in the chamber, or for sampling gas, or for determining gas characteristics.
EFFECT: obtaining a system for determining the interaction between a test atmosphere and a respiratory tract model.
16 cl, 3 dwg
Title | Year | Author | Number |
---|---|---|---|
PERFORATED CONSTRUCTION | 2020 |
|
RU2810805C2 |
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ADVANCED CELL CULTURE DEVICE | 2018 |
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BIOPROCESSING SYSTEMS AND METHODS | 2019 |
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PORT FOR FEEDING TEST CHEMICAL COMPOUND AND WITHDRAWAL OF FLUID FROM CELLS FOR CULTIVATION OF CELL MODELS | 2015 |
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AUTOMATIC DEVICE AND AUTOMATED METHOD FOR CELL CULTURING | 2013 |
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RU2644231C2 |
DEVICE OF MICRO FLUID SYSTEM VALVES PNEUMATIC CONTROL | 2015 |
|
RU2592687C1 |
Authors
Dates
2022-06-24—Published
2018-07-13—Filed