METHOD FOR PRODUCING A COORDINATION COMPOUND OF COPPER(II) WITH 2,3,4,5-TETRAHYDRO-2-IMINO-4-OXO-1,3-THIAZOLE-5-ACETIC ACID Russian patent published in 2022 - IPC C07F1/08 A61K31/426 A61K31/555 A61P35/00 

Abstract RU 2774950 C1

FIELD: chemistry.

SUBSTANCE: invention relates to synthesis of chemical substances, namely, to synthesis of a coordination compound of copper(II) with 2,3,4,5-tetrahydro-2-imino-4-oxo-1,3-thiazole-5-acetic acid. Proposed method includes the interaction of a metal ion with a ligand in a two-component solvent, followed by separating the precipitate, wherein water : ethanol with a volume ratio 1:1 of the components are taken as a two-component solvent, the interaction is performed by electrolysis of a solution containing 2,3,4,5-tetrahydro-2-imino-4-oxo-1,3-thiazole-5-acetic acid and an equimolar amount of sodium hydroxide, with copper electrodes, wherein the mass ratio of water : ethanol : sodium hydroxide : 2,3,4,5-tetrahydro-2-imino-4-oxo-1,3-thiazole-5-acetic acid is 25.00:19.73:0.37:1.60, the DC density is 8 mA/cm2.

EFFECT: creation of a complex compound of copper(II) with 2,3,4,5-tetrahydro-2-imino-4-oxo-1,3-thiazole-5-acetic acid in a single stage, with low time consumption, without using toxic solvents, potentially applicable as therapeutic agents, inter alia antitumour products.

1 cl, 4 dwg, 4 tbl, 1 ex

Similar patents RU2774950C1

Title Year Author Number
METHOD FOR ELECTROCHEMICAL PREPARATION OF ZINC (II) COORDINATION COMPOUND 2021
  • Zelenov Valerij Igorevich
  • Dotsenko Viktor Viktorovich
  • Andrijchenko Elena Olegovna
  • Bovyka Valentina Evgenevna
RU2780198C1
THIAZOLBENZOHETEROCYCLES, METHODS OF THEIR SYNTHESIS, MEDICINAL AGENT, INTERMEDIATE SUBSTANCES FOR SYNTHESIS OF THIAZOLBENZOHETEROCYCLES 1998
  • Ardi Zhan-Klod
  • Bukerel' Zhan
  • Nemesek Patrik
  • Pejronel' Zhan-Fransua
RU2198889C2
CONDENSED BENZAZEPINE DERIVATIVE, AN INTERMEDIATE COMPOUND FOR ITS SYNTHESIS, A PHARMACEUTICAL COMPOSITION 1994
  • Akikhiro Tanaka
  • Khirojuki Kosio
  • Nobuaki Taniguti
  • Akira Matsukhisa
  • Ken-Itiro Sakamoto
  • Atsuki Jamazaki
  • Takejuki Jatsu
RU2129123C1
METHOD OF PRODUCING TETRA-1,10-PHENANTHROLINE-μ-FUMARATE-DICOOPER(II) CHLORIDE 2019
  • Zelenov Valerij Igorevich
  • Andrijchenko Elena Olegovna
  • Sinetskaya Lyudmila Vladimirovna
  • Bovyka Valentina Evgenevna
RU2702119C1
METHOD OF OBTAINING THE COORDINATION CONNECTION OF ZINC WITH NICOTINE ACID 2016
  • Zelenov Valerij Igorevich
  • Andrijchenko Elena Olegovna
  • Tkachev Nikita Vladimirovich
RU2618533C1
TETRAHYDROIMIDAZO-[1,4]-BENZODIAZEPINES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS OR STEREOISOMERS, A METHOD OF THEIR SYNTHESIS, INTERMEDIATE COMPOUNDS FOR THEIR SYNTHESIS AND ANTIVIRAL COMPOSITION 1992
  • Mikhail Zhozef Kjukla[Us]
  • Anri Zhozef Breslin[Us]
  • Al'Fons German Margarita Rajmaker[Be]
  • Zhozefjus Ljudovikjus Jubertjus Van Gelder[Be]
  • Pol' Adrian Zhan Zhansen[Be]
RU2099341C1
THRβ RECEPTOR AGONIST AND METHOD OF ITS OBTAINING AND USE 2019
  • Yu, Shanghai
  • Li, Ben
RU2809040C2
(3-CYCLOALKYL-2, 3, 4, 5 - TETRAHYDRO-1H-BENZO [d] AZEPIN-7-YLOXY) DERIVATIVES, USE THEREOF FOR INHIBITING H3 RECEPTORS, PHARMACEUTICAL COMPOSITION AND PREPARATION METHOD 2003
  • Bamford Mark Dzhejms
  • Din Dehvid Kennet
  • Sekhmi Sandzhit Singkh
  • Uilson Dehvid Mehtt'Ju
  • Vizerington Dzhejson
RU2388752C2
SOLID BENZAZEPIN COMPOUND SALTS AND THEIR USE IN PREPARATION OF PHARMACEUTICAL COMPOUNDS 2003
  • Van Der Ehrden Joris A.
  • De Jong Paulus P. G.
  • Van Der Mej Paulus F. K.
RU2303041C2
LACTAM DERIVATIVE OF PHYSIOLOCICALLY ACCEPTABLE SALTS OR SOLVATES 1992
  • Jan Garal'D Kouts[Gb]
  • Aleksandr Uil'Jam Oksford[Gb]
  • Piter Charl'Z Nort[Gb]
  • Barri Dzhon Prajs[Gb]
RU2081117C1

RU 2 774 950 C1

Authors

Zelenov Valerij Igorevich

Dotsenko Viktor Viktorovich

Andrijchenko Elena Olegovna

Bovyka Valentina Evgenevna

Dates

2022-06-24Published

2021-06-10Filed