FIELD: chemistry.
SUBSTANCE: invention relates to synthesis of chemical substances, namely, to synthesis of a coordination compound of copper(II) with 2,3,4,5-tetrahydro-2-imino-4-oxo-1,3-thiazole-5-acetic acid. Proposed method includes the interaction of a metal ion with a ligand in a two-component solvent, followed by separating the precipitate, wherein water : ethanol with a volume ratio 1:1 of the components are taken as a two-component solvent, the interaction is performed by electrolysis of a solution containing 2,3,4,5-tetrahydro-2-imino-4-oxo-1,3-thiazole-5-acetic acid and an equimolar amount of sodium hydroxide, with copper electrodes, wherein the mass ratio of water : ethanol : sodium hydroxide : 2,3,4,5-tetrahydro-2-imino-4-oxo-1,3-thiazole-5-acetic acid is 25.00:19.73:0.37:1.60, the DC density is 8 mA/cm2.
EFFECT: creation of a complex compound of copper(II) with 2,3,4,5-tetrahydro-2-imino-4-oxo-1,3-thiazole-5-acetic acid in a single stage, with low time consumption, without using toxic solvents, potentially applicable as therapeutic agents, inter alia antitumour products.
1 cl, 4 dwg, 4 tbl, 1 ex
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Authors
Dates
2022-06-24—Published
2021-06-10—Filed