FIELD: medicine.
SUBSTANCE: invention relates to the field of medicine, namely obstetrics and gynecology, and can be used to predict the rate of hemoglobin degradation in a fetus with hemolytic disease after intrauterine intravascular blood transfusion. To do this, the partial pressure of carbon dioxide, the level of lactate, the C3 component of the complement in the umbilical cord blood of the fetus taken during cordocentesis preceding intrauterine intravascular blood transfusion is determined. Next, the prognostic index D is calculated using the original mathematical formula. At a value of D≤-0.18, a high rate of hemoglobin degradation in the fetus is predicted. At a value of D >-0.18, it is concluded that there is no risk of a high rate of hemoglobin degradation in the fetus.
EFFECT: method makes it possible to predict a high rate of hemoglobin degradation by calculating a prognostic index, which optimizes the timing of repeated intrauterine hemotransfusions.
1 cl, 3 ex
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Authors
Dates
2022-08-22—Published
2021-11-09—Filed