FIELD: medicine.
SUBSTANCE: invention relates to medicine, namely to medical diagnostics, and can be used to predict the risk of developing H. pylori-positive gastric ulcer (GU) in unrelated Russian individuals, natives of the Central Black Earth region of the Russian Federation. Venous blood is taken, DNA is isolated from peripheral venous blood, and polymorphic loci rs17576-rs3787268-rs2250889-rs17577 of the MMP-9 gene are analyzed. When the GACG haplotype of polymorphic loci rs17576-rs3787268-rs2250889-rs17577 of the MMP-9 gene is detected, a high risk of developing H. pylori-positive GU is predicted.
EFFECT: method provides for obtaining new criteria for assessing the risk of developing H. pylori-positive GU in individuals of Russian nationality, natives of the Central Black Earth region of the Russian Federation, based on data on polymorphic loci rs17576-rs3787268-rs2250889-rs17577 of the MMP-9 gene.
1 cl, 4 dwg, 4 ex
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