FIELD: medicine; clinical oncology; medical genetics; molecular diagnostics.
SUBSTANCE: isolate DNA from the peripheral venous blood. Analyze polymorphisms. If TCGGCG haplotype of polymorphic loci rs3918242-rs3918249-rs17576-rs3787268-rs2250889-rs17577 of the MMP-9 gene is detected, high risk of developing breast cancer of stages 1-2 in women is predicted.
EFFECT: method provides obtaining new criteria for assessment of breast cancer stage 1-2 risk development in patients of Russian nationality, natives of the Central Black Earth region of the Russian Federation, based on data on polymorphic loci rs3918242-rs3918249-rs17576-rs3787268-rs2250889-rs17577 of the MMP-9 gene.
1 cl, 2 dwg, 6 ex
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