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2 782 111

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IPC

G01N33/68(2006-01-01)

G01N33/569(2006-01-01)

G01N33/573(2006-01-01)

(21) (22)

Application

2022107369, 2022-03-21

(24)

Start date

2022-03-21

(22)

Actual filing date

2022-03-21

(45)

Published

2022-10-21

(72)

Inventor

Andrievskaia Irina AnatolevnaIshutina Nataliia AleksandrovnaDovzhikova Inna ViktorovnaDorofienko Nikolai NikolaevichPrikhodko Nikolai Gennadevich

(73)

Holder

Federalnoe Gosudarstvennoe Biudzhetnoe Nauchnoe Uchrezhdenie Nauchnyi Tsentr Fiziologii I Patologii Dykhaniia»

METHOD FOR ASSESSING VIOLATIONS OF TROPHOBLAST INVASION BY EXAMINING MATRIX METALLOPROTEINASE-9 IN THE VILLOUS CHORION IN CYTOMEGALOVIRUS INFECTION Russian patent published in 2022 - IPC G01N33/68 G01N33/569 G01N33/573

Abstract RU 2782111 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to obstetrics, and can be used to assess violations of trophoblast invasion in women with spontaneous miscarriage associated with cytomegalovirus infection by examining the chorionic villous homogenate by enzyme immunoassay. In the homogenate of the villous chorion determine the content of matrix metalloproteinase-9 (MMP-9). If the MMP-9 value is equal to or less than 19.21 ng/ml, a conclusion is made about a violation of trophoblast invasion.

EFFECT: method provides an opportunity to assess trophoblast invasion in women with spontaneous miscarriage associated with cytomegalovirus infection by determining the MMP-9 content in the chorionic villous homogenate.

1 cl, 2 ex

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RU 2 782 111 C1

Authors

Andrievskaia Irina Anatolevna

Ishutina Nataliia Aleksandrovna

Dovzhikova Inna Viktorovna

Dorofienko Nikolai Nikolaevich

Prikhodko Nikolai Gennadevich

Dates

2022-10-21—Published

2022-03-21—Filed