FIELD: pharmaceutical industry.
SUBSTANCE: peptide compound is proposed, consisting of an amino acid sequence WFGFTGSL or KLNRRWWFGFTGSL, having a capability of inducing apoptosis in a tumor cell, which can be used as a therapeutic agent for the treatment of diseases related to impaired expression of cathepsin S and/or proteins of BCL-2 family. The invention also relates to the use of a peptide compound for induction of apoptosis in a tumor cell, for preparation of a drug causing induction of apoptosis in a tumor cell, as well as to a pharmaceutical composition for induction of apoptosis in a tumor cell, containing the specified peptide compound and a pharmaceutically acceptable carrier.
EFFECT: obtainment of peptide compounds for induction of apoptosis in a tumor cell.
4 cl, 8 dwg, 7 ex
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Authors
Dates
2022-12-13—Published
2021-05-17—Filed