PEPTIDE COMPOUNDS FOR INDUCTION OF APOPTOSIS IN TUMOR CELL Russian patent published in 2022 - IPC C07K7/06 C07K7/08 A61K38/08 A61K38/10 A61P35/00 

Abstract RU 2785794 C2

FIELD: pharmaceutical industry.

SUBSTANCE: peptide compound is proposed, consisting of an amino acid sequence WFGFTGSL or KLNRRWWFGFTGSL, having a capability of inducing apoptosis in a tumor cell, which can be used as a therapeutic agent for the treatment of diseases related to impaired expression of cathepsin S and/or proteins of BCL-2 family. The invention also relates to the use of a peptide compound for induction of apoptosis in a tumor cell, for preparation of a drug causing induction of apoptosis in a tumor cell, as well as to a pharmaceutical composition for induction of apoptosis in a tumor cell, containing the specified peptide compound and a pharmaceutically acceptable carrier.

EFFECT: obtainment of peptide compounds for induction of apoptosis in a tumor cell.

4 cl, 8 dwg, 7 ex

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RU 2 785 794 C2

Authors

Zamiatnin Andrei Aleksandrovich

Surinder Mokhan Sund

Savvateeva Liudmila Vladimirovna

Tarasov Vadim Vladimirovich

Dates

2022-12-13Published

2021-05-17Filed