FIELD: biotechnology.
SUBSTANCE: group of inventions is described, including a composition for use in the treatment or prevention of an inflammatory, autoimmune, or infectious disease or disorder in a subject who needs it (options), a method for the production of a composition (options), and a method for purification of a composition (options). In one of implementations, the composition contains homodimer obtained by a recombinant method and homodimer multimer, wherein homodimer contains two monomers, each of which contains a sequence SEQ ID NO: 4, wherein homodimer does not contain an antigen-binding domain.
EFFECT: invention expands the arsenal of remedies for use in the treatment or prevention of an inflammatory, autoimmune, or infectious disease or disorder in a subject.
35 cl, 51 dwg, 17 tbl, 16 ex
| Title |
Year |
Author |
Number |
| HYBRID PROTEINS OF HUMAN PROTEIN FRAGMENTS TO CREATE ORDERED MULTIMERIZED COMPOSITIONS OF IMMUNOGLOBULIN FC REGIONS WITH ENHANCED BINDING WITH A COMPLEMENT SYSTEM |
2016 |
- Block, David S.
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|
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| HYBRID PROTEINS OF HUMAN PROTEIN FRAGMENTS FOR CREATING ORDERLY MULTIMERIZED COMPOSITIONS OF Fc REGIONS OF IMMUNOGLOBULINS WITH ENHANCED BINDING TO COMPLEMENT SYSTEM |
2016 |
- Block, David S.
- Olsen, Henrik
|
RU2837284C2 |
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2017 |
- Block, David S.
- Olsen, Henrik
|
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| TRIFUNCTIONAL ANTIGEN-BINDING MOLECULE |
2015 |
- Litl Melvin
- Zhukovski Evgenij
- Ezer Markus
- Vajkhel Majkl
- Gantke Torsten
- Rojsh Uve
- Ellvanger Kristina
- Le Gall Fabrik
|
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| METHODS FOR CULTIVATION OF CELLS AND SETS AND DEVICE FOR THEM |
2016 |
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- Gref Patritsiya
|
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| METHODS, SETS, MEANS AND DEVICES FOR TRANSDUCTION |
2016 |
- Tarin, Semikh, U.
- Bashur, Kinan
|
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| IMMUNOGLOBULIN CONSTANT REGION FC-RECEPTOR BINDING AGENTS |
2008 |
- Strome Scott E.
- Schulze Dan H.
- Block David S.
- Olsen Henrik
|
RU2729829C2 |
| ANTIBODY PURIFICATION |
2019 |
- Iskra, Timoti
- Sakramo, Eshli Margaret
|
RU2812161C2 |
| OLIGOMERIC REAGENTS IN FORM OF PARTICLES AND THEIR APPLICATION METHODS |
2018 |
- Schmidt, Thomas
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- Prentice, Ken
|
RU2777989C2 |
| DEVELOPMENT OF STABLE HETERODIMERIC ANTIBODY WITH MUTATIONS IN Fc DOMAIN |
2012 |
- Shpreter Fon Kredenshtajn, Tomas
- Diksit, Serzhit Bkhimarao
- Eskobar-Kabrera, Erik
- Lario, Pola Iren
- Pun, Devid Kaj Yuen
|
RU2810540C2 |
