OPTIMIZATION OF MANUFACTURE OF GL-2045 MULTIMERIZED STRADOMER Russian patent published in 2023 - IPC C07K14/47 C07K1/14 C07K16/28 C07K16/18 C07K16/32 C07K16/46 C12P21/08 A61K39/395 A61K47/64 A61P35/00 A61P37/00 

Abstract RU 2790232 C2

FIELD: biotechnology.

SUBSTANCE: group of inventions is described, including a composition for use in the treatment or prevention of an inflammatory, autoimmune, or infectious disease or disorder in a subject who needs it (options), a method for the production of a composition (options), and a method for purification of a composition (options). In one of implementations, the composition contains homodimer obtained by a recombinant method and homodimer multimer, wherein homodimer contains two monomers, each of which contains a sequence SEQ ID NO: 4, wherein homodimer does not contain an antigen-binding domain.

EFFECT: invention expands the arsenal of remedies for use in the treatment or prevention of an inflammatory, autoimmune, or infectious disease or disorder in a subject.

35 cl, 51 dwg, 17 tbl, 16 ex

Similar patents RU2790232C2

Title Year Author Number
HYBRID PROTEINS OF HUMAN PROTEIN FRAGMENTS TO CREATE ORDERED MULTIMERIZED COMPOSITIONS OF IMMUNOGLOBULIN FC REGIONS WITH ENHANCED BINDING WITH A COMPLEMENT SYSTEM 2016
  • Block, David S.
  • Olsen, Henrik
RU2737378C2
METHOD FOR TREATMENT OF INFLAMMATORY DISEASES WITH MULTIVALENT Fc COMPOUNDS 2017
  • Block, David S.
  • Olsen, Henrik
RU2774318C2
TRIFUNCTIONAL ANTIGEN-BINDING MOLECULE 2015
  • Litl Melvin
  • Zhukovski Evgenij
  • Ezer Markus
  • Vajkhel Majkl
  • Gantke Torsten
  • Rojsh Uve
  • Ellvanger Kristina
  • Le Gall Fabrik
RU2753882C2
METHODS FOR CULTIVATION OF CELLS AND SETS AND DEVICE FOR THEM 2016
  • Germerot Lotar
  • Shtemberger Kristian
  • Gref Patritsiya
RU2778411C2
METHODS, SETS, MEANS AND DEVICES FOR TRANSDUCTION 2016
  • Tarin, Semikh, U.
  • Bashur, Kinan
RU2761555C2
IMMUNOGLOBULIN CONSTANT REGION FC-RECEPTOR BINDING AGENTS 2008
  • Strome Scott E.
  • Schulze Dan H.
  • Block David S.
  • Olsen Henrik
RU2729829C2
ANTIBODY PURIFICATION 2019
  • Iskra, Timoti
  • Sakramo, Eshli Margaret
RU2812161C2
OLIGOMERIC REAGENTS IN FORM OF PARTICLES AND THEIR APPLICATION METHODS 2018
  • Schmidt, Thomas
  • Stemberger, Christian
  • Kowski, Tom
  • Prentice, Ken
RU2777989C2
METHODS FOR CELL CULTIVATION AND SETS AND DEVICE FOR THEM 2016
  • Germerot, Lotar
  • Shtemberger, Kristian
  • Gref, Patritsiya
  • Bashur, Kinan
RU2761557C2
DEVELOPMENT OF STABLE HETERODIMERIC ANTIBODY WITH MUTATIONS IN Fc DOMAIN 2012
  • Shpreter Fon Kredenshtajn, Tomas
  • Diksit, Serzhit Bkhimarao
  • Eskobar-Kabrera, Erik
  • Lario, Pola Iren
  • Pun, Devid Kaj Yuen
RU2810540C2

RU 2 790 232 C2

Authors

Block, David S.

Merigeon, Emmanuel Y.

Olsen, Henrik

Dates

2023-02-15Published

2017-12-08Filed