FIELD: biotechnology.
SUBSTANCE: invention relates to the field of biotechnology, in particular to methods for the production of a cell composition. Methods include obtainment of an input cell composition, bringing of the input cell composition into contact with an agent including a nucleic acid molecule encoding a recombinant receptor, as well as stimulation of the input cell composition before, during, or after the specified contact.
EFFECT: invention is effective for the production of a uniform and/or predictable T-cell product and/or a product with lower toxicity compared to other methods.
89 cl, 3 dwg, 3 tbl, 4 ex
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