FIELD: measurement system.
SUBSTANCE: methods for determining the concentration of an analyte in a liquid sample of a physiological fluid. Method for determining analyte concentration in a fluid sample of a physiological fluid, the method comprising the steps of applying the sample to a biosensor, the biosensor comprising an electrochemical cell having electrodes; applying a predetermined voltage waveform including the first predetermined voltage applied for at least the first time interval and the second predetermined voltage applied for the second time interval to the biosensor electrodes; measuring at least the first current values during the first time interval and the second current values during the second time interval, in which the current ipb, representing the transition from the first predetermined voltage to the second predetermined voltage, occurs during the initial part of the second time interval; determining the time of the turning point during the first time interval in which the measured first current values pass from the first profile to the second profile; and calculating the analyte concentration in the sample based on the determined turning point time and at least one current value from the first and the second measured current values, wherein the first measured current values transition from the first profile to the second profile due to the presence of an interference in the fluid sample, and wherein the turning point time occurs before the occurrence of ipb.
EFFECT: increase of the accuracy of analyte concentration measurements carried out in presence of interferents in a sample of physiological fluid.
19 cl, 22 dwg, 7 tbl
