FIELD: medicine.
SUBSTANCE: invention relates to cardiology, therapy, rehabilitation, and can be used to predict the progression of heart failure in patients with obstructive sleep apnea. DNA is isolated from the buccal epithelium. The polymorphic locus rs3918242 is determined using the real-time polymerase chain reaction method followed by allele typing of the matrix metalloproteinase-9 gene. In the presence of a heterozygous genotype, the risk of progression of heart failure in its carriers is predicted.
EFFECT: method improves the accuracy of disease prognosis by determining the heterozygous genotype of the polymorphic locus rs3918242 of the matrix metalloproteinase-9 gene.
1 cl, 1 dwg, 4 tbl, 2 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PREDICTION OF ATRIAL FIBRILLATION DEVELOPMENT IN PATIENTS WITH OBSTRUCTIVE SLEEP APNEA SYNDROME | 2022 |
|
RU2793677C1 |
| METHOD FOR PREDICTING THE ONE-YEAR RISK OF ADVERSE CARDIOVASCULAR EVENTS IN MEN AFTER DECOMPENSATION OF CHRONIC HEART FAILURE WITH PRESERVED LEFT VENTRICULAR EJECTION FRACTION AND OBSTRUCTIVE SLEEP APNEA SYNDROME | 2021 |
|
RU2767266C1 |
| METHOD FOR PREDICTING PROGRESSION OF ANTHRACYCLINE-INDUCED CHRONIC HEART FAILURE IN PATIENTS WITH BREAST CANCER WITHIN 24 MONTHS | 2022 |
|
RU2793672C1 |
| METHOD FOR HUMAN GENOTYPE DETERMINATION BY POLYMORPHISM IN MATRIX METALLOPROTEINASE 3 (MMR3) -11715A/6A GENE | 2018 |
|
RU2699053C1 |
| METHOD FOR ORTHOGNATHIC SURGERY WITH MAXILLA-MANDIBULAR EXTENSION FOR PERSONS WITH OBSTRUCTIVE SLEEP APNEA SYNDROME | 2016 |
|
RU2635827C1 |
| METHOD OF DETERMINING INDICATIONS FOR POLYSOMNOGRAPHIC EXAMINATION OF PATIENTS WITH ARTERIAL HYPERTENSION | 2007 |
|
RU2372025C2 |
| METHOD FOR PREDICTION OF INCREASED RICK OF DEVELOPING STAGE 1-2 BREAST CANCER IN WOMEN BASED ON POLYMORPHISM OF THE MATRIX METALLOPROTEINASE 9 GENE | 2022 |
|
RU2795100C1 |
| METHOD FOR PREDICTION OF ANTHRACYCLINE-INDUCED CARDIOTOXICITY IN WOMEN WITH BREAST CANCER | 2019 |
|
RU2714683C1 |
| METHOD FOR PREDICTION OF UNFAVOURABLE OUTCOME OF HYPERTROPHIC CARDIOMYOPATHY | 2013 |
|
RU2527768C1 |
| METHOD FOR PREDICTING RISK OF GRADE 3 MALIGNANCY OF TUMOR CELLS IN BREAST CANCER | 2023 |
|
RU2823459C1 |
