METHOD FOR PREDICTING THE EFFECTIVENESS OF BASIC THERAPY OF MILD BRONCHIAL ASTHMA WITH A COMBINATION OF EXTRA-FINE BECLOMETHASONE DIPROPIONATE/FORMOTEROL FUMARATE Russian patent published in 2023 - IPC A61B5/87 A61K9/12 A61K31/542 A61P11/06 

Abstract RU 2796466 C1

FIELD: medicine; pulmonology.

SUBSTANCE: invention relates to medicine, namely to pulmonology, and can be used to predict the effectiveness of basic therapy of mild bronchial asthma with a combination of extra-fine beclomethasone dipropionate /formoterol fumarate. To do this, using spirography, the value of MOS75 is determined. The quality of life indicator is calculated according to the "Symptoms" scale of the AQLQ questionnaire, the level of asthma control according to the Asthma Control Test questionnaire ACT. The value of the discriminant function (D) is determined by the equation according to the developed mathematical formula. Then, the value of the discriminant function is compared with its boundary value equal to -10.33, and the effectiveness of basic therapy of bronchial asthma with a dosed aerosol of extra-fine beclomethasone dipropionate /formoterol fumarate is predicted. If the value of D is greater than the boundary value of the discriminant function, it is predicted that bronchial asthma control will be achieved within 3 months when treated with a dosed aerosol of extra-fine beclomethasone dipropionate /formoterol fumarate. When the value of D is less than or equal to the boundary value of the discriminant function is predicted to be unable to control bronchial asthma for 3 months when treated with a dosed aerosol of extra-fine beclomethasone dipropionate/formoterol fumarate.

EFFECT: invention makes it possible to predict the effectiveness of basic therapy of AD with a dosed aerosol of extra-fine beclomethasone dipropionate/ formoterol fumarate without using a bronchodilator test of isocapnic hyperventilation with cold air, to optimize treatment tactics in patients with asthma with impaired patency of the small respiratory tract, it is reasonable to prescribe to these patients a drug – a dosed aerosol for inhalation of extra-fine beclomethasone dipropionate / formoterol fumarate for basic therapy of asthma, significantly reduce the timing of the selection of the optimal treatment method.

1 cl, 2 ex

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RU 2 796 466 C1

Authors

Perelman Natalia Lvovna

Kolosov Viktor Pavlovich

Dates

2023-05-24Published

2022-07-29Filed