LIGHT-RESISTANT IMITATION OF MACULAR PIGMENT Russian patent published in 2023 - IPC C07D335/12 C09B11/28 C09B23/01 C09B69/10 G02B1/04 G02C7/04 C08K5/45 

FIELD: ophthalmology.

SUBSTANCE: invention relates to a compound of formula II, where EWG in each case represents cyano; n is either 1, 2 or 3; a R¹ is independently H, C₁-C ₆ alkyl, C₁-C₆ alkoxy, C₁-C₆ thioalkyl, C₃-C₇ cycloalkyl, phenyl, halogen, hydroxy, amino, NR³R⁴, benzyl, SO₃H or SO₃M (M is a monovalent cation such as sodium or potassium) or -Y-P_g where R³ and R⁴ are independently H or C₁-C ₆ alkyl, Y in each occurrence independently represents either C₁-C₈ alkylene or C₁-C₈ oxaalkylene; and P_g at each occurrence is independently (meth)acrylate, (meth)acrylamide, N-vinyl lactam, N-vinylamide, or styryl; wherein the compound contains 1 or 2 -Y-P_g groups, which may or may not be the same. The invention relates to an ophthalmic device, which is a contact lens containing a compound of formula II according to the invention. The invention also relates to a contact lens based on the compound of formula II according to the invention.

EFFECT: compound having maximum absorption of visible light in the range of 430–480 nm and full width at half height (FWHM) at maximum absorption of visible light of at least 35 nm and up to 100 nm, moreover, the connection is light stable when measured in accordance with ICH Q1B guidance.

13 cl, 2 dwg, 3 tbl, 4 ex