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2 801 117

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IPC

C12N5/76(2010-01-01)

A61B17/425(2006-01-01)

A61P15/08(2006-01-01)

(21) (22)

Application

2022131354, 2022-12-01

(24)

Start date

2022-12-01

(22)

Actual filing date

2022-12-01

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Published

2023-08-02

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Inventor

Sysoeva Anastasiya PavlovnaMakarova Natalya PetrovnaSilachev Denis NikolaevichNepsha Oksana SergeevnaGoryunov Kirill VladimirovichShevtsova Yuliya AleksandrovnaKalinina Elena AnatolevnaSukhikh Gennadij Tikhonovich

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Uchrezhdenie Meditsinskij Issledovatelskij Tsentr Akusherstva, Ginekologii I Perinatologii Imeni Akademika V.I. Kulakova" Ministerstva Zdravookhraneniya Rossijskoj Federatsii

METHOD OF SELECTION OF MALE GAMETES USING EXTRACELLULAR VESICLES OF FOLLICULAR FLUID DURING FERTILIZATION BY METHOD OF INTRACYTOPLASMATIC SPERMATOZOID INJECTION INTO OOCYTE Russian patent published in 2023 - IPC C12N5/76 A61B17/425 A61P15/08 

Abstract RU 2801117 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to a method of selecting sperm during ICSI fertilization. The method involves the isolation of extracellular vesicles from the follicular fluid and their adding to a modified Petri dish for ICSI, in which an additional reservoir with extracellular vesicles of the follicular fluid is created.

EFFECT: method is effective for the selection of fertile spermatozoa and the treatment of infertility in ART cycles.

1 cl, 1 dwg, 2 ex

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RU 2 801 117 C1

Authors

Sysoeva Anastasiya Pavlovna

Makarova Natalya Petrovna

Silachev Denis Nikolaevich

Nepsha Oksana Sergeevna

Goryunov Kirill Vladimirovich

Shevtsova Yuliya Aleksandrovna

Kalinina Elena Anatolevna

Sukhikh Gennadij Tikhonovich

Dates

2023-08-02—Published

2022-12-01—Filed

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