FIELD: medicine, experimental obstetrics and gynecology.
SUBSTANCE: nitrofen is administered weekly to rats after female and male rats are placed together. On the 9th day after mating, rats undergo an ultrasound examination (ultrasound) confirming pregnancy and assessing the size of the fetus. After confirmation of 9-day pregnancy, weekly oral administration of nitrofen is stopped. On the 21st day of pregnancy, the fetuses of rats are removed from the uterus by surgery.
EFFECT: method allows to obtain a model for studying the pathogenesis of congenital diaphragmatic hernia, the formation of changes in the lung tissue, the study of drugs for the correction of lung hypoplasia.
1 cl, 2 tbl, 4 dwg, 1 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR CORRECTION OF PULMONARY HYPOPLASIA IN FETUS CONGENITAL DIAPHRAGMATIC HERNIA IN RATS USING SELECTIVE INHIBITOR OF SPECIFIC PDE-5 CGMP | 2022 |
|
RU2801604C1 |
| METHOD OF MINIMALLY INVASIVE INTRAUTROBIAL BALLOON OCCLUSION OF FETAL TRACHEA WITH DIAPHRAGMATIC HERNIA IN FATAL PULMONARY HYPOPLASIA | 2016 |
|
RU2669727C2 |
| METHOD OF DETERMINING INDICATIONS FOR BALLOON OCCLUSION OF TRACHEA IN FOETUS LUNG HYPOPLASIA | 2017 |
|
RU2710325C2 |
| METHOD OF PRENATAL PREDICTION OF STATE OF NEWBORN BABY WITH CONGENITAL DIAPHRAGMATIC HERNIA | 2011 |
|
RU2476156C1 |
| METHOD FOR ULTRASOUND DIAGNOSTICS OF AFFECTED DEVELOPMENT OF FETAL LUNGS | 2005 |
|
RU2284151C1 |
| METHOD FOR POST MORTEM DIAGNOSTICS OF PULMONARY HYPOPLASIA IN NEWBORN | 2017 |
|
RU2637171C1 |
| METHOD FOR DIAGNOSING LUNG HYPOPLASIA IN A DECEASED NEWBORN PATHWAY AFTER POSTMORTEM MAGNETIC RESONANCE IMAGING | 2017 |
|
RU2650981C1 |
| METHOD FOR MINIMALLY INVASIVE INTRAUTERINE BYPASS OF LARGE CYSTS WITH COMPLICATED CYSTIC ADENOMATOUS LUNG DEFECT IN THE FETUS | 2022 |
|
RU2786327C1 |
| POLYTETRAFLUOROEHTYLENE IMPLANT AND METHODS OF THORACOSCOPIC PLASTY OF DIAPHRAGM IN NEWBORNS OR CHILDREN OF EARLY AGE WITH APPLICATION OF IMPLANT | 2011 |
|
RU2456958C1 |
| METHOD OF INTRAUTONEAL TRACHEA BALLOON OCCLUSION IN FETUS WITH CONGENITAL DIAPHRAGMIC HERNIATION AND LUNG HYPOPLASIA OF THE FETUS AND DEVICE FOR ITS IMPLEMENTATION | 2022 |
|
RU2797631C1 |
