FIELD: pharmaceuticals; medicine.
SUBSTANCE: invention provides obtaining a dispersible tablet that releases an active pharmaceutical ingredient (APS) belonging to one of the following classes: BCS 2 or BCS 4 at an increased rate due to the inclusion of API in amorphous form in a combined delivery system (CDS) consisting of various poloxamers and magnesium aluminometasilicate as a solid dispersion medium, which has a synergistic effect in preferred embodiments of the invention.
EFFECT: significant increase in the release rate of APS and an increase in the stability of the solid dispersion system APS-poloxamer during storage.
4 cl, 14 tbl, 5 ex
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