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RU

(11)

2 805 825

(13)

C1

(51)

IPC

G01N33/58(2006-01-01)

C12Q1/6806(2018-01-01)

C12Q1/6827(2018-01-01)

C12Q1/686(2018-01-01)

C12Q1/6883(2018-01-01)

(21) (22)

Application

2022133496, 2022-12-20

(24)

Start date

2022-12-20

(22)

Actual filing date

2022-12-20

(45)

Published

2023-10-24

(72)

Inventor

Evseeva Galina PetrovnaTelepneva Regina SergeevnaNagovitsyna Elena BorisovnaSuprun Evgenii NikolaevichSuprun Stefaniia ViktorovnaLebedko Olga Antonovna

(73)

Holder

Federalnoe Gosudarstvennoe Biudzhetnoe Nauchnoe Uchrezhdenie Nauchnyi Tsentr Fiziologii I Patologii Dykhaniia»

METHOD OF PREDICTING RISK OF UNCONTROLLED BRONCHIAL ASTHMA IN OBESE CHILDREN Russian patent published in 2023 - IPC G01N33/58 C12Q1/6806 C12Q1/6827 C12Q1/686 C12Q1/6883 

Abstract RU 2805825 C1

FIELD: medicine; pediatrics; pulmonology.

SUBSTANCE: invention can be used to predict the uncontrolled course of bronchial asthma in obese children. Using real-time PCR analysis, polymorphic variants rs1042713 (Arg16Gly) in the ADRB2 gene and rs1801282 (Pro12Ala) in the PPARG gene are studied. When a combination of genotype AG or GG of the polymorphic variant rs1042713 (Arg16Gly) of the ADRB2 gene and genotype CG or GG of the polymorphic variant rs1801282 (Pro12Ala) of the PPARG gene is detected, the uncontrolled course of bronchial asthma is predicted.

EFFECT: method provides new criteria for assessing the risk of uncontrolled bronchial asthma in obese children based on combinations of metabolic genes.

1 cl, 1 dwg, 3 ex

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RU 2 805 825 C1

Authors

Evseeva Galina Petrovna

Telepneva Regina Sergeevna

Nagovitsyna Elena Borisovna

Suprun Evgenii Nikolaevich

Suprun Stefaniia Viktorovna

Lebedko Olga Antonovna

Dates

2023-10-24—Published

2022-12-20—Filed

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