Patenton — panteon of patents

(19)

RU

(11)

2 806 116

(13)

C1

(51)

IPC

C07D213/66(2006-01-01)

C07C233/47(2006-01-01)

A61K31/195(2006-01-01)

A61K31/4412(2006-01-01)

A61P19/10(2006-01-01)

(21) (22)

Application

2023102529, 2023-02-06

(24)

Start date

2023-02-06

(22)

Actual filing date

2023-02-06

(45)

Published

2023-10-26

(72)

Inventor

Trunov Konstantin SergeevichDanilenko Anton PavlovichSkachilova Sofiia IakovlevnaGudyrev Oleg SergeevichDanilenko Liudmila MikhailovnaPokrovskii Mikhail VladimirovichSimakina Ekaterina AleksandrovnaErmakova Galina AleksandrovnaShilova Elena VladimirovnaNadezhdin Sergei ViktorovichKhentov Aleksei AleksandrovichMalorodova Tatiana NikolaevnaBoeva Elizaveta ValerevnaCherednichenko Albina ViacheslavovnaShcheblykina Olesia ViktorovnaMiller Eduard Sergeevich

(73)

Holder

Federalnoe Gosudarstvennoe Avtonomnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniia Gosudarstvennyi Natsionalnyi Issledovatelskii Universitet"

PHARMACOLOGICAL COMPOUND BASED ON 2-ETHYL-6-METHYL-3-HYDROXYPYRIDINIUM N-ACETYL-6-AMINOHEXANOATE AND 2-ETHYL-6-METHYL-3-HYDROXYPYRIDINIUM 3-PYRIDINOCARBONOATE AND ITS USE FOR CORRECTION AND PREVENTION OF OSTEOPOROSIS Russian patent published in 2023 - IPC C07D213/66 C07C233/47 A61K31/195 A61K31/4412 A61P19/10 

Abstract RU 2806116 C1

FIELD: organic chemistry, medicine and experimental pharmacology.

SUBSTANCE: group of inventions relates to a new compound with osteoprotective activity. The pharmacological compound of 2-ethyl-6-methyl-3-hydroxypyridinium N-acetyl-6-aminohexanoate and 2-ethyl-6-methyl-3-hydroxypyridinium 3-pyridinocarbonoate, in a ratio of 1:3, C62H94N8O15, compound 1, which has osteoprotective activity is disclosed. Also the following is disclosed: the use of the above-mentioned pharmacological compound 1, which provides effective correction and prevention of osteoporosis.

Compound 1

EFFECT: group of inventions provides effective correction and prevention of osteoporosis.

2 cl, 4 tbl, 1 ex

Similar patents RU2806116C1

Title Year Author Number
METHOD FOR CORRECTING OSTEOPOROSIS AND OSTEOPOROTIC FRACTURES WITH 2-ETHYL-6-METHYL-3-HYDROXYPYRIDINIUM HYDROXYBUTANEDIOATE IN EXPERIMENT 2021
  • Trunov Konstantin Sergeevich
  • Skachilova Sofiya Yakovlevna
  • Gudyrev Oleg Sergeevich
  • Danilenko Lyudmila Mikhajlovna
  • Pokrovskij Mikhail Vladimirovich
  • Simakina Ekaterina Aleksandrovna
  • Danilenko Anton Pavlovich
  • Shilova Elena Vladimirovna
  • Stefanova Marina Sergeevna
  • Yakushev Vladimir Ivanovich
  • Gureev Vladimir Vladimirovich
  • Martynova Olga Viktorovna
 RU2775439C1
METHOD FOR THE CORRECTION OF OSTEOPOROSIS AND OSTEOPOROTIC FRACTURES WITH 3-HYDROXY-2-ETHYL-6-METHYLPYRIDINIUM NICOTINATE IN EXPERIMENT 2021
  • Trunov Konstantin Sergeevich
  • Skachilova Sofiya Yakovlevna
  • Gudyrev Oleg Sergeevich
  • Danilenko Lyudmila Mikhajlovna
  • Pokrovskij Mikhail Vladimirovich
  • Simakina Ekaterina Aleksandrovna
  • Danilenko Anton Pavlovich
  • Shilova Elena Vladimirovna
  • Stefanova Marina Sergeevna
  • Yakushev Vladimir Ivanovich
  • Gureev Vladimir Vladimirovich
  • Martynova Olga Viktorovna
 RU2763011C1
METHOD FOR RESERVATROL-BASED OSTEOPOROSIS CORRECTION AND FRAGILITY FRACTURE PREVENTION 2010
  • Pokrovskij Mikhail Vladimirovich
  • Gudyrev Oleg Sergeevich
  • Fajtel'Son Aleksandr Vladimirovich
  • Koklina Natal'Ja Jur'Evna
  • Artjushkova Elena Borisovna
  • Pokrovskaja Tat'Jana Grigor'Evna
  • Korokin Mikhail Viktorovich
  • Korokina Lilija Viktorovna
  • Belous Aleksandr Sergeevich
  • Kochkarov Vladimir Iskhakovich
  • Danilenko Ljudmila Mikhajlovna
  • Gladchenko Mikhail Petrovich
  • Gureev Vladimir Vladimirovich
  • Kolesnik Inga Mikhajlovna
  • Stabrovskaja Nadezhda Vladimirovna
  • Ragulina Vera Alekseevna
  • Ivanov Aleksandr Viktorovich
  • Jakushev Vladimir Ivanovich
 RU2437161C1
METHOD FOR RESERVATROL AND ENALAPRIL BASED OSTEOPOROSIS CORRECTION AND FRAGILITY FRACTURE PREVENTION 2010
  • Pokrovskij Mikhail Vladimirovich
  • Gudyrev Oleg Sergeevich
  • Fajtel'Son Aleksandr Vladimirovich
  • Koklina Natal'Ja Jur'Evna
  • Artjushkova Elena Borisovna
  • Pokrovskaja Tat'Jana Grigor'Evna
  • Korokin Mikhail Viktorovich
  • Korokina Lilija Viktorovna
  • Belous Aleksandr Sergeevich
  • Kochkarov Vladimir Iskhakovich
  • Danilenko Ljudmila Mikhajlovna
  • Gladchenko Mikhail Petrovich
  • Gureev Vladimir Vladimirovich
  • Kolesnik Inga Mikhajlovna
  • Stabrovskaja Nadezhda Vladimirovna
  • Ragulina Vera Alekseevna
  • Ivanov Aleksandr Viktorovich
  • Jakushev Vladimir Ivanovich
 RU2437160C1
COMPLEX SALTS OF ACIDUM ACEXAMICUM, STIMULATING REGENERATION OF BONE TISSUE, ACCELERATING PROCESSES OF REPARATIVE OSTEOGENESIS, STIMULATING MINERALIZATION OF BONE TISSUE IN OSTEOPOROSIS 2018
  • Skachilova Sofiya Yakovlevna
  • Ermakova Galina Aleksandrovna
  • Blinova Ekaterina Valerievna
  • Blinov Dmitrij Sergeevich
  • Rufova Larisa Vasilevna
  • Shilova Elena Vladimirovna
  • Dydykin Sergej Sergeevich
  • Kovalenko Polina Sergeevna
  • Zheltukhin Nikolaj Konstantinovich
  • Korotonozhkin Aleksej Viktorovich
 RU2668966C1
METHOD FOR CORRECTING MICROCIRCULATORY DISORDERS WITH 2-ETHYL-6-METHYL-3-HYDROXYPYRIDINIUM 5-HYDROXY-3-PYRIDINOCARBONATE IN EXPERIMENTAL NMDA-MEDIATED EXCITOTOXICITY IN THE RETINA 2022
  • Solovev Nikolaj Vadimovich
  • Pobeda Anna Sergeevna
  • Skachilova Sofiya Yakovlevna
  • Gureev Vladimir Vladimirovich
  • Simakina Ekaterina Aleksandrovna
  • Yurochkina Aleksandra Mikhajlovna
  • Peresypkina Anna Aleksandrovna
  • Bashuk Viktoriya Vladimirovna
  • Pokrovskij Mikhail Vladimirovich
  • Proskurina Oksana Vladimirovna
  • Shilova Elena Vladimirovna
  • Chernyaeva Sofya Sergeevna
  • Kostina Darya Aleksandrovna
  • Kochkarova Indira Sultanovna
  • Efimenko Svetlana Vladimirovna
  • Lebedeva Darya Sergeevna
 RU2784350C1
METHOD FOR CORRECTING BONE MICROCIRCULATION ACCOMPANYING OSTEOPOROSIS AND UNDERLYING FRACTURES WITH USE OF COMBINATION OF L-ARGININE AND LOSARTAN 2013
  • Gudyrev Oleg Sergeevich
  • Radzhkumar Densing Samuehl Radzh
  • Fajtel'Son Aleksandr Vladimirovich
  • Pokrovskij Mikhail Vladimirovich
  • Remizov Pavel Pavlovich
  • Sobolev Mikhail Sergeevich
  • Pokrovskaja Tat'Jana Grigor'Evna
  • Korokin Mikhail Viktorovich
  • Kochkarov Vladimir Iskhakovich
  • Arustamova Anna Aleksandrovna
 RU2542425C1
METHOD FOR ROSUVASTATIN CORRECTION OF BONE MICROCIRCULATION IN EXPERIMENTAL OSTEOPOROSIS AND ACCOMPANYING FRACTURES 2013
  • Gudyrev Oleg Sergeevich
  • Remizov Pavel Pavlovich
  • Sobolev Mikhail Sergeevich
  • Fajtel'Son Aleksandr Vladimirovich
  • Pokrovskij Mikhail Vladimirovich
  • Radzhkumar Densing Samuehl Radzh
  • Pokrovskaja Tat'Jana Grigor'Evna
  • Korokin Mikhail Viktorovich
  • Kochkarov Vladimir Iskhakovich
  • Arustamova Anna Aleksandrovna
 RU2538612C1
METHOD FOR CORRECTION OF BONE TISSUE MICROCIRCULATON IN EXPERIMENTAL OSTEOPOROSIS AND ASSOCIATED FRACTURES WITH COMBINATION OF RECOMBINANT ERYTHROPOIETIN AND ROSUVASTATIN 2013
  • Gudyrev Oleg Sergeevich
  • Remizov Pavel Pavlovich
  • Sobolev Mikhail Sergeevich
  • Fajtel'Son Aleksandr Vladimirovich
  • Pokrovskij Mikhail Vladimirovich
  • Radzhkumar Densing Samuehl Radzh
  • Pokrovskaja Tat'Jana Grigor'Evna
  • Korokin Mikhail Viktorovich
  • Kochkarov Vladimir Iskhakovich
  • Arustamova Anna Aleksandrovna
 RU2541184C1
METHOD OF OSTEOPOROSIS CORRECTION AND PREVENTION OF OSTEOPOROTIC FRACTURES BY MEANS OF LOSARTAN 2008
  • Pokrovskij Mikhail Vladimirovich
  • Gudyrev Oleg Sergeevich
  • Fajtel'Son Aleksandr Vladimirovich
  • Dubrovin Grigorij Mendelevich
  • Artjushkova Elena Borisovna
  • Pokrovskaja Tat'Jana Grigor'Evna
  • Korokin Mikhail Viktorovich
  • Belous Aleksandr Sergeevich
  • Kochkarov Vladimir Iskhakovich
  • Danilenko Ljudmila Mikhajlovna
  • Gladchenko Mikhail Petrovich
  • Gureev Vladimir Vladimirovich
  • Koklina Natal'Ja Jur'Evna
 RU2369391C1

RU 2 806 116 C1

Authors

Trunov Konstantin Sergeevich

Danilenko Anton Pavlovich

Skachilova Sofiia Iakovlevna

Gudyrev Oleg Sergeevich

Danilenko Liudmila Mikhailovna

Pokrovskii Mikhail Vladimirovich

Simakina Ekaterina Aleksandrovna

Ermakova Galina Aleksandrovna

Shilova Elena Vladimirovna

Nadezhdin Sergei Viktorovich

Khentov Aleksei Aleksandrovich

Malorodova Tatiana Nikolaevna

Boeva Elizaveta Valerevna

Cherednichenko Albina Viacheslavovna

Shcheblykina Olesia Viktorovna

Miller Eduard Sergeevich

Dates

2023-10-26—Published

2023-02-06—Filed

read Similar patents