METHOD FOR REMOVING EXTRACELLULAR NANOVESICLES FROM BLOOD PLASMA USING COVALENTLY IMMOBILIZED DNA APTAMERS Russian patent published in 2023 - IPC C12N5/00 B82B3/00 G01N33/48

Abstract RU 2806434 C1

FIELD: biotechnology.

SUBSTANCE: method for removing extracellular nanosized vesicles from blood plasma. The method is distinguished by the use of DNA aptamers, covalently immobilized on the surface of a biocompatible matrix, as ligands for sorption of vesicles, the spatial structure of which ensures specific and effective binding of the components of the surface membrane of nanovesicles.

EFFECT: expanding the scope of methods for removing extracellular nanovesicles from blood plasma for use in the field of efferent therapy methods or therapeutic plasma absorption.

2 cl, 2 dwg, 4 tbl, 3 ex

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RU 2 806 434 C1

Authors

Malek Anastasiia Valerevna

Dates

2023-10-31—Published

2022-08-10—Filed