FIELD: medicine.
SUBSTANCE: invention relates to medicine, in particular to medical diagnostics, and is intended to predict the risk of developing preeclampsia (PE). In unrelated Russian individuals, a native of the Central Black Earth region of the Russian Federation, DNA is isolated from peripheral venous blood. An analysis of polymorphisms of the PPP1R12C gene differentially expressed in the placenta is carried out. An increased risk of developing PE is predicted by the detection of the CA haplotype of the haploblock rs2532058-rs66707428 of the PPP1R12C gene.
EFFECT: invention provides an effective method for predicting the risk of developing PE in pregnant women of Russian nationality, a native of the Central Black Earth region of the Russian Federation.
1 cl, 1 tbl, 4 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PREDICTING THE RISK OF DEVELOPING PREECLAMPSIA BASED ON MOLECULAR GENETIC ANALYSIS | 2021 |
|
RU2775433C1 |
| METHOD FOR PREDICTING THE WEIGHT OF A NEWBORN, TAKING INTO ACCOUNT GENETIC FACTORS | 2021 |
|
RU2775436C1 |
| METHOD FOR PREDICTING THE RISK OF DEVELOPMENT OF PREECLAMPSIA IN PREGNANT WOMEN WITH FETAL GROWTH RESTRICTION SYNDROME | 2021 |
|
RU2754956C1 |
| METHOD OF PREDICTING RISK OF DEVELOPING PREECLAMPSIA IN PREGNANT WOMEN WITH FETAL GROWTH RESTRICTION | 2023 |
|
RU2808924C1 |
| METHOD FOR PREDICTION OF RISK OF DEVELOPING PREECLAMPSIA WITH UNDERLYING GESTATIONAL DIABETES MELLITUS IN PATIENTS AFTER USING ASSISTED REPRODUCTIVE TECHNOLOGIES | 2023 |
|
RU2821559C1 |
| METHOD FOR PREDICTING THE WEIGHT OF A NEWBORN TAKING INTO ACCOUNT THE POLYMORPHIC LOCUS OF HEXOKINASE 2, DIFFERENTIALLY EXPRESSED IN THE PLACENTA | 2021 |
|
RU2786313C1 |
| METHOD FOR FORMING RISK GROUP OF PRE-ECLAMPSIA | 2021 |
|
RU2762204C1 |
| METHOD OF PREDICTING SEVERE PRE-ECLAMPSIA | 2014 |
|
RU2568892C1 |
| METHOD FOR PREDICTING THE RISK OF FETAL GROWTH RETARDATION | 2021 |
|
RU2775435C1 |
| METHOD FOR PREDICTING THE RISK OF DEVELOPING PRIMARY OPEN-ANGLE GLAUCOMA IN WOMEN | 2021 |
|
RU2775431C1 |
