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2 810 437

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IPC

G09B23/28(2006-01-01)

(21) (22)

Application

2023116325, 2023-06-21

(24)

Start date

2023-06-21

(22)

Actual filing date

2023-06-21

(45)

Published

2023-12-27

(72)

Inventor

Pashkovskaia Oksana AleksandrovnaSergeevichev David SergeevichKrasilnikov Sergei EduardovichMurashov Ivan Sergeevich

(73)

Holder

Federalnoe Gosudarstvennoe Biudzhetnoe Uchrezhdenie Meditsinskii Issledovatelskii Tsentr Imeni Akademika E.N. Meshalkina" Ministerstva Zdravookhraneniia Rossiiskoi Federatsii

METHOD OF MODELING ACUTE POST-RADIATION PNEUMONITIS IN LABORATORY ANIMALS Russian patent published in 2023 - IPC G09B23/28 

Abstract RU 2810437 C1

FIELD: medicine.

SUBSTANCE: invention relates to a method of modeling acute post-radiation pneumonitis in laboratory animals. The method is characterized by the following: intraperitoneal anesthesia is performed, topometric scanning is performed using computed tomography, the irradiation zones and the size of the absorbed dose are determined, and the animal is irradiated. X-ray irradiation is carried out from two opposite positions of the irradiator at a total dose of 16 Gy with a dose rate of 3 Gy/min in the area of the middle lobe of the left lung in an orthogonal projection.

EFFECT: invention provides modeling of acute post-radiation pneumonitis in laboratory animals, which has radiological and morphohistological signs characteristic of acute post-radiation pneumonitis in humans after high-dose ionizing irradiation of the lungs.

1 cl, 1 dwg

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RU 2 810 437 C1

Authors

Pashkovskaia Oksana Aleksandrovna

Sergeevichev David Sergeevich

Krasilnikov Sergei Eduardovich

Murashov Ivan Sergeevich

Dates

2023-12-27—Published

2023-06-21—Filed

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