FIELD: veterinary virology and biotechnology.
SUBSTANCE: invention relates to development of a cultural inactivated emulsion vaccine against foot and mouth disease from O No. 2620/Orenburgsky/2021 strain of O/ME-SA/Ind-2001e genotype. The vaccine contains an avirulent and purified concentrated antigen of O No. 2620/Orenburgsky/2021 strain of O/ME-SA/Ind-2001e genotype obtained in a suspension transplanted cell line from the kidney of a new-born Syrian hamster (BHK-21/SUSP/ARRIAH), representing a suspension containing predominantly 146S immunogenic component of FMDV and Montanide ISA-61 VG oil adjuvant in effective ratios.
EFFECT: vaccine is highly immunogenic and safe, it can provide effective protection against a homologous infectious agent circulating in Asian countries.
2 cl, 1 dwg, 8 tbl, 13 ex
| Title | Year | Author | Number |
|---|---|---|---|
| O N 2620/ORENBURG/2021 STRAIN OF FOOT AND MOUTH DISEASE VIRUS APHTAE EPIZOOTICAE GENOTYPE O/ME-SA/IND-2001E FOR PRODUCTION OF BIOLOGICAL PRODUCTS FOR DIAGNOSIS AND SPECIFIC PREVENTION OF FOOT AND MOUTH DISEASE | 2023 |
|
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| CULTURAL INACTIVATED EMULSION VACCINE AGAINST FOOT-AND-MOUTH DISEASE SEROTYPE O FROM STRAIN "O/ARRIAH/MYA-98" | 2023 |
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RU2816944C1 |
| APHTAE EPIZOOTICAE FOOT-AND-MOUTH DISEASE VIRUS STRAIN "O NO 2222/TAIWAN/1/2012" FOR PRODUCTION OF BIOPREPARATIONS FOR DIAGNOSIS AND SPECIFIC PREVENTION OF FOOT-AND-MOUTH DISEASE | 2023 |
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RU2817031C1 |
| O/KENYA/2017 STRAIN OF FMD VIRUS APHTAE EPIZOOTICAE GENOTYPE O/EA-2 FOR THE MANUFACTURE OF BIOLOGICAL PRODUCTS FOR THE DIAGNOSIS AND SPECIFIC PREVENTION OF FMD GENOTYPE O/EA-2 | 2022 |
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| CULTURAL INACTIVATED SORBED VACCINE AGAINST FOOT-AND-MOUTH DISEASE FROM THE STRAIN "A/EGYPT/EURO-SA/2022" | 2023 |
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RU2817381C1 |
