METHOD FOR DIFFERENTIAL DIAGNOSIS OF DRUG-INDUCED TOXIC AND INFECTIOUS PULMONARY INVOLVEMENT IN ONCOHEMATOLOGICAL PATIENTS Russian patent published in 2024 - IPC A61B5/00 A61B6/03 G01N33/48 

FIELD: medicine.

SUBSTANCE: invention can be used for differential diagnosis of drug-induced pulmonary involvement (DIPI) and infectious pulmonary involvement in oncohematological patients. Patient is evaluated for presence of a diagnosis of lymphoma, allergy or autoimmune disease in history, period after allogenic hematopoietic stem cell transplantation is more than 30 days, presence of shortness of breath, absence of body temperature increase, absence of concurrent mucositis, non-increased level of C-reactive protein of serum, high level of serum creatinine, non-reduced number of leukocytes in blood, high number of eosinophils in blood, absence of local infiltrative changes according to results of chest computed tomography, absence of changed bronchial walls according to results of chest computed tomography. If observing each of the signs, 1 point is assigned to it. Points are summed up. If the total score is less than 5, a low probability of DIPI is diagnosed. If the total score is from 5 to 7 inclusive, the average probability of DIPI is determined. If total score is 8 and more, DIPI is highly probable.

EFFECT: method provides an objective and accessible differential diagnosis of pulmonary involvement in oncohematological patients, possesses high sensitivity and specificity due to evaluation of the most significant diagnostic parameters.

1 cl, 2 dwg, 3 ex