DEVICE FOR QUANTIFYING GLUCOSE CONTENT IN PHYSIOLOGICAL FLUIDS Russian patent published in 2024 - IPC G01N1/02 G01N31/22 G01N27/07 G01N27/327 C12M1/42 

FIELD: biotechnology.

SUBSTANCE: invention relates to the field of biotechnology, namely to biosensor analytical devices, and can be used to quantify the glucose content in physiological fluids, in particular in blood, plasma and serum. The device contains a graphite printed electrode, the surface of which is modified with a hybrid composite material having inclusions of the enzyme glucose oxidase. In this case, the hybrid composite material contains an organosilicon matrix including (3-aminopropyl)triethoxysilane and tetraethoxysilane in volume ratios of 20:80 and covalently bound to a mediator in the form of Nile blue, as well as inclusions of polyvinyl alcohol and carbon nanotubes placed in the matrix.

EFFECT: invention makes it possible to increase the upper limit of the determined glucose concentrations in physiological fluids to 1.4 mmol/dm³.

1 cl, 5 dwg, 2 tbl