DEVICE FOR QUANTIFYING GLUCOSE CONTENT IN PHYSIOLOGICAL FLUIDS Russian patent published in 2024 - IPC G01N1/02 G01N31/22 G01N27/07 G01N27/327 C12M1/42 

FIELD: biotechnology.

SUBSTANCE: invention relates to the field of biotechnology, namely to biosensor analytical devices, and can be used to quantify the glucose content in physiological fluids, in particular in blood, plasma and serum. The device contains a graphite printed electrode, the surface of which is modified with a hybrid composite material having inclusions of the enzyme glucose oxidase. In this case, the hybrid composite material contains an organosilicon matrix of tetraethoxysilane and inclusions of single-walled carbon nanotubes placed in this matrix, inclusions of a chitosan-based redoxactive polymer covalently bound to the Nile blue mediator.

EFFECT: invention allows to increase the operating time of the device for quantifying the glucose content in physiological fluids without replacing the hybrid composite material while maintaining high sensitivity indicators with respect to the glucose content in physiological fluids. 1 cl, 5 dwg, 2 tbl