FIELD: biotechnology.
SUBSTANCE: invention relates to the field of biotechnology, namely to biosensor analytical devices, and can be used to quantify the glucose content in physiological fluids, in particular in blood, plasma and serum. The device contains a graphite printed electrode, the surface of which is modified with a hybrid composite material having inclusions of the enzyme glucose oxidase. In this case, a redox-active polymer based on chitosan covalently bound to a mediator in the form of Nile blue is used as a hybrid composite material.
EFFECT: invention makes it possible to expand the range of detectable glucose concentrations to 0.006-1.0 mM.
1 cl, 5 dwg, 2 tbl
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Authors
Dates
2024-07-23—Published
2024-04-11—Filed