FIELD: medicine.
SUBSTANCE: invention can be used for diagnosis and determination of prodromal stage of Parkinson's disease. Disclosed is a method for determining the prodromal stage of PD by detecting early motor disorders, characterized by the fact that average parameters of movements of a group of patients with early stage of PD are determined by means of registration and analysis of trajectories of simple movements of separate organs and their joint coordinated movements; average statistical parameters of movements of a group of healthy subjects are determined by recording and analyzing trajectories of simple movements of separate organs and their joint coordinated movements; determining the movement parameters of the subject from the risk group by recording and analyzing the trajectories of simple movements of separate organs and their joint coordinated movements; when analyzing the results, the emergence of a persistent trend of the value or values of the movement parameters of the subject from the risk group in relation to the values of the control group towards those of the patients with early stage of PD is detected, which indicates a prodromal stage of PD in this subject.
EFFECT: invention provides the possibility of determining the forthcoming PD at the earliest (prediagnostic) stages of its development, id est detecting the prodromal stage of PD.
1 cl, 4 dwg
Title | Year | Author | Number |
---|---|---|---|
METHOD AND DEVICE FOR DIAGNOSING HUMAN MOTOR ACTIVITY | 1999 |
|
RU2146494C1 |
METHOD FOR DIAGNOSING CENTRAL VESTIBULAR DISORDERS CHARACTERISTIC OF THE EARLY STAGE OF PARKINSON'S DISEASE | 2017 |
|
RU2657963C1 |
METHOD FOR DIFFERENTIAL DIAGNOSIS OF ESSENTIAL TREMOR AND EARLY AND FIRST STAGES OF PARKINSON'S DISEASE BY ANALYSING FLARE-LIKE ACTIVITY OF MUSCLES | 2020 |
|
RU2741233C1 |
METHOD FOR EARLY PRECLINICAL DIAGNOSTICS OF PARKINSON'S DISEASE BY CONCENTRATION OF CATECHOLAMINES IN PATIENT'S LACRIMAL FLUID | 2019 |
|
RU2775261C2 |
DIFFERENTIAL DIAGNOSTIC TECHNIQUE FOR PARKINSONIAN DISEASE AND ESSENTIAL TREMOR | 2011 |
|
RU2467697C1 |
METHOD FOR DETERMINING PARKINSON DISEASE TREATMENT EFFECTIVENESS | 2004 |
|
RU2285441C2 |
METHOD OF DIAGNOSTICS OF VISUAL DYSFUNCTION IN PARKINSON'S DISEASE UNDER MEDICATED CORRECTION | 2018 |
|
RU2677068C1 |
METHOD FOR ESTIMATING STATUS OF MOTOR FUNCTION OF HAND | 2008 |
|
RU2371088C1 |
COMPLEX DIAGNOSTIC TECHNIQUE FOR MOTOR AND MENTAL FUNCTIONS IN PATIENTS SUFFERING ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY | 2011 |
|
RU2467686C2 |
DIAGNOSTIC TECHNIQUE FOR PARKINSON DISEASE IN PATIENTS WITH OLFACTORY DYSFUNCTION | 2011 |
|
RU2478209C1 |
Authors
Dates
2024-09-09—Published
2023-10-23—Filed