METHOD OF PRODUCING OSTEOPLASTIC DISPERSE BIOCOMPOSITE Russian patent published in 2021 - IPC A61K6/00 A61L27/10 A61L27/12 C04B35/16 C04B35/447 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to methods for producing bioresorbable osteoplastic biocomposites of synthetic type, intended for treating diseases and injuries of the human bone system, and can be used in dentistry and maxillofacial surgery. Method provides for production of osteoplastic disperse biocomposite based on hydroxyapatite and wollastonite by means of sol-gel synthesis using calcium-, phosphorus-, silicon-containing aqueous solutions as precursors and involves mixing the precursor mixture-containing reaction mixture to obtain a precipitate in the form of gel, separating, washing, drying and calcining the obtained precipitate. At the step of sol-gel synthesis, the internal porous volume of the obtained biocomposite is structured by adding siloxane-acrylate latex and carbon fiber into the reaction mixture as pore-forming components. Further, the obtained material is thermo-oxidative treated to form a crystalline phase and remove the blowing agents by heating in an air atmosphere at rate of 5 °C/min to temperature 800 °C with holding at the achieved temperature for 55–65 minutes.

EFFECT: technical result is higher biological activity of the obtained disperse osteoplastic composite of wollastonite/hydroxyapatite by lowering the calcination temperature and reducing its duration, as well as by conducting the process in controlled conditions.

3 cl, 2 ex, 3 tbl, 2 dwg