FIELD: organic chemistry, vitamins. SUBSTANCE: invention relates to new derivatives of vitamin D amide of the general formula (Ia) R1,R2 where values A, Y, 
are given in p. 1 of the invention claim that show inhibitory activity with respect to the cellular proliferation. Invention describes also a pharmaceutical composition based on the compound of the formula (Ia) that inhibits cell the proliferation and can be used for treatment of patients with neoplastic diseases. EFFECT: enhanced effectiveness of compounds. 8 cl, 1 tbl, 12 ex
| Title | Year | Author | Number |
|---|---|---|---|
| 22-THIAVITAMIN D DERIVATIVES, METHOD OF PREPARATION THEREOF, METHOD FOR PREPARATION OF COMPOUNDS, AND COMPOUNDS | 1995 |
|
RU2142941C1 |
| DERIVATIVES OF VITAMIN D, COMPOUNDS PHARMACEUTICAL COMPOSITION, THERAPEUTIC AGENT, TREATMENT METHOD | 2001 |
|
RU2230738C9 |
| CARBONYLATION METHOD | 2001 |
|
RU2323926C2 |
| ANALOGS OF VITAMIN D, METHOD OF THEIR SYNTHESIS, DIASTEREO- -ISOMER, PHARMACEUTICAL COMPOSITION | 1993 |
|
RU2163234C2 |
| VITAMIN D ANALOG | 1991 |
|
RU2037484C1 |
| ANALOGS OF VITAMIN D, METHODS OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION | 1993 |
|
RU2136660C1 |
| BICYCLIC HETEROCYCLIC SPIROCOMPOUNDS | 2010 |
|
RU2506266C2 |
| NEW COMPOUNDS AS POTENTIAL INDUCERS OF TERMINAL DIFFERENTIATION OF TUMOR CELLS, A PHARMACEUTICAL COMPOSITION BASED ON SAID | 1992 |
|
RU2128643C1 |
| ANALOGUES OF VITAMIN D, COMPOSITIONS CONTAINING INDICATED ANALOGUES AND THEIR USING | 2003 |
|
RU2320644C2 |
| 9,10-SECOPREGNANE DERIVATIVE AND PHARMACEUTICAL AGENTS | 2007 |
|
RU2440980C2 |
